Medusa

With: Cyclops (Blue Team)

Cyclops (Blue Team): +10% Attack Rating for each Champion Cyclops defeats in a Quest. Max: 5. Other Synergy Champions: Damaging Debuffs gain 20% increased potency.

With: Dracula

Medusa: +20% Combat Adrenaline. Dracula: Gain the bonuses of other present Synergy Champions.

With: Gladiator

All Champions: +155 Critical Rating.

With: Human Torch

All Champions: +5% Combat Power Rate.

With: Karnak

All Champions: +6% Health.

With: Maestro (Cosmic)

All Champions: +115 Critical Damage Rating.

With: Okoye

Synergy Champions: +3% Health and +3% Attack Rating. Once per fight, Evading an attack, Landing a Heavy Attack, or Knocking the Opponent down with a Special Attack grants +7% Attack Rating until the end of the fight.

With: Scream

Scream: A successful personal Auto-Block grants 1 additional copy of the currently selected Hybrid Buff. Medusa: When a personal Armor Shattered effect ends, inflict a 475 Armor Break Debuff for 4 seconds for each personal Fury Buff.

With: She-Hulk (Deathless)

Synergy Champions: For each unique Synergy Champion on the team, all Champions gain +50 Critical Damage Rating and +80 Block Proficiency.

With: Vox

Vox: For each #Inhuman a Vox has defeated over the course of the Quest, they start each fight with a Corrupted Inhuman Royal Family: Start each fight with an indefinite Fury Buff for each #Inhuman a Vox has defeated over the course of the Quest, each granting 100% Attack Rating.