Spider-Man (Stark Enhanced)

With: Doctor Octopus

All Champions: +6% Attack Rating.

With: Doctor Strange

Doctor Strange: +40% increased Nullify Ability Accuracy. Spider-Man (Stark Enhanced): Start each fight by inflicting a Shock Debuff dealing 400% of Attack as Energy Damage over 30 seconds. Synergy Champions: There is a 1 in 14,000,605 chance to also start with an indefinite +1000% Fury Buff.

With: Green Goblin

Green Goblin: +15% Pumpkin Bomb damage for each Cunning and Madness charge. Spider-Man Champions: Critical Hits generate 15% more Power.

With: Iron Man (Infinity War)

Everyone: Enemies are 35% less likely to evade Basic Attacks

With: Lizard

All Champions: +155 Critical Rating.

With: Maestro (Cosmic)

All Champions: +115 Critical Damage Rating.

With: Mister Negative

#Spider-Verse Heroes: Start the fight with 2 indefinite Passive Dark Energy

With: Mysterio

All Champions: +8% Attack Rating.

With: Red Goblin

All Champions: +6% Attack Rating.

With: Sandman

Spider-Man (Stark Enhanced): Increases the EMP Webshot’s Power Drain potency by 15% Sandman: While the Opponent is Decelerated by Sandman’s Special Attack 2, Sandman cannot Miss.

With: Scorpion

Scorpion: +15% Perfect Block Chance while Scorpion-Sense is active. Spider-Man (Stark Enhanced): Refreshing a Taunt by Dodging Back and Idling for 1 second also inflicts a Cowardice Debuff on the Opponent reducing Special Attack Damage by 25% for 10 seconds.

With: Shocker

Synergy Champions: Medium Attacks inflict a Damage Over Time Debuff dealing 20% of Attack over 2 seconds. The type of Debuff is specific to each Synergy Champion. Shocker: Shock Debuffs. Spider-Man (Stark Enchanced): Rupture Debuffs.

With: Spider-Ham

All Champions: +5% Perfect Block Chance.

With: Spider-Man (Classic)

#Spider-Verse Heroes: Gain a 10% chance to Evade. Does not trigger while Blocking, except against Unblockable attacks.

With: Spider-Man (Supreme)

Spider-Man (Supreme): Buffs granted by Blessing of the Web Spider-Man (Stark Enhanced): Reduces the EMP Webshot cooldown by 7.5 second(s).

With: Spider-Man 2099

Spider-Man 2099: Second Medium attacks have a 25% chance to trigger Spider-Man 2099 Debuff Pausing ability. Spider-Man (Stark Enhanced): On a Well Timed Block 33% chance to gain a Bulwark Passive, granting 700 Block Proficiency for 10 second(s).

With: Spider-Slayer (J. Jonah Jameson)

Spider-Slayer (J. Jonah Jameson): Start each fight furious with 1 personal Fury Passive. This effect does not stack with duplicate synergies. All Champions: +155 Critical Rating.

With: Vulture

All Champions: +6% Attack Rating.

With: War Machine

All Champions: +5% Perfect Block Chance.