Thanos

With: Galan

Galan: Converting Resistances into Planetary Mass creates an additional 5 Planetary Mass per Resistance. Thanos: The first time Thanos would be knocked out in each fight, he gains an Indestructible Buff, keeping the Mad Titan alive for 8 seconds.

With: Jessica Jones

Synergy Champions: Filling a Bar of Power randomly grants a dormant Unblockable, True Damage, or 40% Prowess Charge. Charges are removed and replaced with their corresponding Buffs during this Champion’s next Special Attack. Jessica Jones: Striking a Champion who has an active Unblockable, True Damage, or Prowess effect grants a Fury Passive, increasing Attack Rating by 30% for 8 seconds

With: Maestro (Cosmic)

Synergy Champions: +100 Armor Rating, +100 Critical Rating, +100 Critical Damage Rating, and +3% Perfect Block Chance, doubled when fighting the final node in a Quest.

With: Mantis

All Champions: +155 Critical Rating.

With: Nebula

All Champions: +6% Health.

With: Odin

All Champions: +155 Critical Rating.

With: Spider-Gwen

All Champions: +155 Critical Rating.

With: Squirrel Girl

Squirrel Girl: When Tippy-Toe would Purify all non-damaging Debuffs on Squirrel Girl, also Purify 1 damaging Debuff(s). This can only be used once per fight. Thanos: +10% Attack Rating while fighting Hero Champions.

With: Star-Lord (Stellar-Forged)

All Champions: +155 Critical Rating.

With: The Overseer

The Overseer: 50% chance to gain an Indefinite Gamma Power when the Opponent launches a Special while taunted. Thanos: Fury also grants a Power Gain Buff, gaining half of a bar of Power over 7 second(s).

With: Ultron (Classic)

All Champions: +115 Critical Damage Rating.

With: Wolverine (Weapon X)

Wolverine (Weapon X): Start the fight with 5 Rage charges. Thanos: Start the fight with a Fury Buff, granting 50% of your Base Attack for 15 Seconds.